Medications for Cerebellar Disorders
Timothy C. Hain, MD
Medications Which Occasionally Help:
Clonazepam (0.5 MG TID).
Halcion (0.5 mg as needed Q 4 H).
Ativan (0.5 mg BID).
These medications are all close relatives. They all are sedating, and all sometimes improve balance.
INH (100 mg TID, increase by 300 mg every 3 days to a toal of 1200 mg. Liver function test every week. Pyridoxine along with INH dose of 50 mg TID). This drug has helped some persons with Multiple Sclerosis and unsteadiness.
TRH (0.5 mg IM every other day). TRH is an "orphan drug". It costs $18.50/ampuoule. It must be given by injection. Results on average are about 1/3 improvement in balance (according to Japanese literature). Improvement starts quickly, and lasts about 2-3 weeks after last injection. This drug is obviously expensive -- costs about $70/week.
Diamox (1-3 tabs/day). This diuretic helps some persons with periodic ataxia.
Medications to avoid:
Stimulants (such as amphetamines)
The first two medications can make normal people unsteady, and unsteady people worse.
Stimulants can cause neurons to "burn out".
Read all labels and avoid medications which have a significant incidence of dizziness, unless specifically advised by your doctor.